He used a 3 days ON followed by 1 day OFF (rest). This is the workout as he describes in his book, “ Flawless”. Not to mention he had phenomenal abdominals. Bob Paris’ Workout Routineīob Paris had a great physique. We’ll supply the intelligent training plan, you supply the hard work and hopefully you picked the right parents. What’s the secret sauce for creating a great body? “It was a combination of hard work, intelligent training, and good genes.” True to Bob Paris bodybuilding philosophy, his workout strived to “Create an aesthetic and beautiful physique as well as maximizing your own potential.” As a result Bob Paris opted out of competitive bodybuilding and focused on building his business empire. Aesthetics and physical beauty of the physique are no longer taken into consideration when it came time to judge the winner of a bodybuilding competition. Abuse of anabolic steroids was rampant and obvious. Throughout the 1980-1990’s bodybuilding went from a celebration of aesthetic physiques to an absolute freak show. Although Paris admitted to using steroids under duress, he did so to a limit and would not sacrifice his athletic looking physique. He was a man that stuck to his guns and refused to compromise his beliefs when the massive muscle masters hit the stage. Unfortunately, Bob Paris was a casualty of an evolving bodybuilding culture. I’m saying their physiques where clearly much larger than their predecessors.) I’m not knocking Haney or Yates’ intelligence, they are both smart guys. Bodybuilding went from a celebration of beauty and aesthetics to a ‘roided out freak show. Mass monsters like Dorian Yates and Lee Haney hit the scene and changed bodybuilding forever. But in the 1980’s things were a changin’. (Actually, all the notable Golden Era bodybuilders had big brains and social skills. He was thinking well ahead into the future and planning for life after bodybuilding, which many athletes fail to do (leading to their ruin).īob Paris smashed the notion that bodybuilders where just a bunch of dumb meatheads. By the time he was 25 years old he already launched his apparel line “Paris Fashions” which tailored to the athletic physique. He was also ahead of his years in terms of maturity. His claim to fame was sculpting a lean, strong, beautiful and aesthetic physique. These data could explain both acute kidney injury in COVID-19 patients and the development of chronic kidney disease in long COVID.Bob Paris is a bodybuilding legend and a fan favorite. Our results suggest that SARS-CoV-2 can directly infect kidney cells and induce cell injury with subsequent fibrosis. A SARS-CoV-2 protease inhibitor was able to ameliorate the infection of kidney cells by SARS-CoV-2. Importantly, SARS-CoV-2 infection also led to increased collagen 1 protein expression in organoids. Single-cell RNA sequencing indicated injury and dedifferentiation of infected cells with activation of profibrotic signaling pathways. To study direct effects of the virus on the kidney independent of systemic effects of COVID-19, we infected human-induced pluripotent stem-cell-derived kidney organoids with SARS-CoV-2. Here, we report that SARS-CoV-2 directly infects kidney cells and is associated with increased tubule-interstitial kidney fibrosis in patient autopsy samples. Kidney failure is frequently observed during and after COVID-19, but it remains elusive whether this is a direct effect of the virus.
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